410.649.2000 Local       

1.800.556.5522 Toll Free


Xeljanz is a Janus kinase (JAK) inhibitor that is commonly prescribed to treat patients with rheumatoid arthritis, psoriatic arthritis and ulcerative colitis by helping to regulate the immune system. The main active ingredient is Toficitinib, which works to block the body’s production of JAKs, a type of intracellular enzyme that influences cellular and immune system processes. About 132,000 individuals were prescribed Xeljanz as a treatment for their rheumatoid arthritis between January 2013 and July 2018.  This number does not include patients who were prescribed Xeljanz for psoriatic arthritis and ulcerative colitis.

What are Harmful Side Effects of Xeljanz?

Xeljanz can cause a variety of common side effects including:

  • Headaches
  • High cholesterol
  • Nausea
  • Rashes
  • Hypertension
  • Shingles
  • Cold-like symptoms

While many of these side effects are not necessarily life-threatening and are common side effects of prescription medication, arthritis and colitis medication Xeljanz can also lead to more severe health conditions like infection, cancer and blood clots.

 Clinical Trials Point to Increased Risk of Blood Clots

On February 25th, 2019, the Food and Drug Administration (FDA) released a safety communication regarding a new study that found an increased risk of developing serious blood clots in the lungs and a higher chance of death in rheumatoid arthritis patients who took higher doses of Xeljanz.

After the FDA released a warning concerning the risk of blood clots, pharmaceutical liability attorneys began accepting cases on behalf of patients who suffered from pulmonary embolisms and deep vein thrombosis, two serious types of blood clots. The FDA received reports of 52 deep vein thrombosis claims and 79 pulmonary embolisms between 2013 and 2018.

Xeljanz is Linked to Additional Serious Side Effects

Between 2013 and 2018, the FDA Adverse Events Reporting System, or FAERS, received 42,528 claims of adverse reactions to Xeljanz and Xeljanz XR, and out of these reactions, 14,679 were severe and 983 resulted in death.

In addition to the risk of developing blood clots, Xeljanz has been found to be linked to other severe and life-threatening side effects including cancers, such as lymphoma, and infections, such as herpes zoster (shingles) and tuberculosis. In addition, Xeljanz causes Hepatitis B or C activation in patients who carry the virus in their bloodstream.

 Xeljanz Victims Have Legal Rights

As more information emerges surrounding the potential increased risk of developing blood clots as well as a multitude of life-threatening cancers and diseases while taking Xeljanz and Xeljanz XR, the legal team at The Law Offices of Peter Angelos urge you to pursue legal action if you have developed a medical issue as a result of taking this prescription drug. It is possible to receive compensation for the medical bills your have collected as a result of requiring treatment for blood clots, infections and other serious health conditions as a result of Xeljanz intake.

The pharmaceutical liability attorneys at The Law Offices of Peter Angelos have decades of experience representing clients who suffered from adverse reactions and severe side effects as a result of taking prescription drugs and can help you pursue the compensation you deserve. If you or a loved one has developed an illness after taking pharmaceutical drug Xeljanz, contact The Law Offices of Peter Angelos today.